Mulundocandin, a new lipopeptide antibiotic. II. Structure elucidation.
نویسندگان
چکیده
The structure of a new antifungal antibiotic, mulundocandin, C48H77N7O16, was elucidated by high field NMR experiments e.g., homo- and heteronuclear correlation spectra, distortionless enhancement by polarization transfer (DEPT) spectra as well as nuclear Overhauser effect. The compound is a lipopeptide antibiotic belonging to the echinocandin class.
منابع مشابه
Mulundocandin, an echinocandin-like lipopeptide antifungal agent: biological activities in vitro.
Mulundocandin (MCN) is an antifungal lipopeptide which belongs to the echinocandin class of antimycotic agents. MCN exhibited good in vitro activity against Candida albicans and C. glabrata isolates with MIC ranges of 0.5-4.0 microg/ml and 2.0-4.0 microg/ml, respectively. MCN also exhibited some activity against C. tropicalis isolates (MIC range 1.0-8.0 microg/ml). However, MCN was poorly activ...
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عنوان ژورنال:
- The Journal of antibiotics
دوره 40 3 شماره
صفحات -
تاریخ انتشار 1987